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(S)-C33

Chemical Structure : (S)-C33

CAS No.: 2066488-39-7

(S)-C33 (C33(S))

Catalog No.: PC-60608Not For Human Use, Lab Use Only.

A novel potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A novel potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms; shows better selectivity than (R)-C33 against PDE5.

Physicochemical Properties

M.Wt 357.842
Formula C18H20ClN5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-6-((1-(4-chlorophenyl)ethyl)amino)-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

References

1. Huang M, et al. Mol Pharmacol. 2015 Nov;88(5):836-45.

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