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(S)-Timolol maleate

Chemical Structure : (S)-Timolol maleate

CAS No.: 26921-17-5

(S)-Timolol maleate (Timolol maleate)

Catalog No.: PC-45202Not For Human Use, Lab Use Only.

A potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.

Hypertension

Approved

Physicochemical Properties

M.Wt 432.4918
Formula C17H28N4O7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 4.4 mg/mL

Chemical Name/SMILES

2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1)

References

1. Mandagere AK, et al. J Med Chem. 2002;45(2):304-11.

2. Aggarwal D, et al. Int J Pharm. 2005 Feb 16;290(1-2):155-9.

3. Borok J, et al. Br J Dermatol. 2017 Aug 3. doi: 10.1111/bjd.15865.

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