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Chemical Structure : (S)93-31
Catalog No.: PC-61239Not For Human Use, Lab Use Only.
(S)93-31 is a pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM).
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(S)93-31 is a pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM).
(S)93-31 maximizes neuroprotection in ischemic tissue while minimizing on-target side effects associated with NMDAR blockade in noninjured brain regions.
| M.Wt | 489.452 | |
| Formula | C22H30Cl2N2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yuan H, et al. Neuron. 2015 Mar 18;85(6):1305-1318.
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