(±)-BI-D |CAS:1416258-16-6 Probechem Biochemicals

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Chemical Structure : (±)-BI-D

CAS No.: 1416258-16-6

(±)-BI-D

Catalog No.: PC-45473Not For Human Use, Lab Use Only.

(±)-BI-D is a potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

(±)-BI-D is a potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.
(±)-BI-D inhibits the replication of NL4.3 virus (T124/T125) with EC50 of 51 nM.

Physicochemical Properties

M.Wt	405.4862
Formula	C25H27NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Quinolineacetic acid, 4-(3,4-dihydro-2H-1-benzopyran-6-yl)-α-(1,1-dimethylethoxy)-2-methyl-

References

1. Fader LD, et al. ACS Med Chem Lett. 2014 Apr 16;5(6):711-6.

2. Wang H, et al. Nucleic Acids Res. 2012 Dec;40(22):11518-30.

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(±)-BI-D

Biological Activity

Physicochemical Properties

References

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