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019854-B06

Chemical Structure : 019854-B06

CAS No.:

019854-B06

Catalog No.: PC-25848Not For Human Use, Lab Use Only.

019854-B06 is a potent tat-binding antiretroviral compound with IC50 of 1.4 and 0.83 uM in F-Luc activity and HIV-1 infection assays, inhibits Tat-dependent transcription phase, shows binding affinity (KD) of 33.5 uM to Tat peptide.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

019854-B06 is a potent tat-binding antiretroviral compound with IC50 of 1.4 and 0.83 uM in F-Luc activity and HIV-1 infection assays, inhibits Tat-dependent transcription phase, shows binding affinity (KD) of 33.5 uM to Tat peptide.

Physicochemical Properties

M.Wt 454.61
Formula C28H38O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

methyl (E)-2-(2-((4-(decyloxy)phenoxy)methyl)phenyl)-3-methoxyacrylate

References

1. Shin Y, et al. Biochemistry. 2025 Nov 28. doi: 10.1021/acs.biochem.5c00203.

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