1-ECBC | Yak1 inhibitor | Probechem Biochemicals

Chemical Structure : 1-ECBC

CAS No.: 72755-19-2

1-ECBC (Kumujian A, 1-Ethoxycarbonyl-β-carboline)

Catalog No.: PC-73393Not For Human Use, Lab Use Only.

1-ECBC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.

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10 mg	$378	In stock
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Biological Activity

1-ECBC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.
1-ECBC blocked C. albicans biofilm formation in several co-culture models and a rat catheter infection model.

Physicochemical Properties

M.Wt	240.262
Formula	C14H12N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-ethoxycarbonyl-beta-carboline

References

1. MacAlpine J, et al. Nat Commun. 2021 Oct 22;12(1):6151.

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1-ECBC (Kumujian A, 1-Ethoxycarbonyl-β-carboline)

Biological Activity

Physicochemical Properties

References

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