Chemical Structure : 1-NM-PP1
CAS No.: 221244-14-0
Catalog No.: PC-26293Not For Human Use, Lab Use Only.
1-NM-PP1 is a cell-permeable PP1 analog and potent Src family kinases inhibitor with IC50 of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively, also inhibits PKD with IC50 of 398 nM (PKD2) and analog-sensitive CRK9 (CRK9AS).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
1-NM-PP1 is a cell-permeable PP1 analog and potent Src family kinases inhibitor with IC50 of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively, also inhibits PKD with IC50 of 398 nM (PKD2) and analog-sensitive CRK9 (CRK9AS).
| M.Wt | 331.42 | |
| Formula | C20H21N5 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-(tert-butyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
|
1. Goyard S, et al. Mol Biol Cell. 2008 May;19(5):2251-66.
2. Plank M, et al. Mol Biol Cell. 2024 Apr 1;35(4):ar60.
3. Bishop AC, et al. Nature. 2000 Sep 21;407(6802):395-401.
4. Gosavi U, et al. Mol Microbiol. 2020 Jun;113(6):1225-1239.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright