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Chemical Structure : 1-Naphthyl PP1 hydrochloride
CAS No.: 956025-47-1
Catalog No.: PC-43793Not For Human Use, Lab Use Only.
A potent Src family kinases with IC50 of 1.0/0.6/0.6 uM for v-Sr/c-Fyn/c-Abl.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $105.6 | In stock | |
| 50 mg | $424.8 | In stock | |
| 100 mg | $720 | In stock |
Bulk size, bulk discount!
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A potent Src family kinases with IC50 of 1.0/0.6/0.6 uM for v-Sr/c-Fyn/c-Abl; less potent for CDK2 and CaMK II; also inhibits Kin28 and Srb10 kinases; potently blocks prostate cancer cell proliferation by inducing G2/M arrest.
| M.Wt | 353.8486 | |
| Formula | C19H20ClN5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 73 mg/mL |
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| Chemical Name/SMILES |
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-, hydrochloride (1:1) |
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1. Bishop AC, et al. Nature. 2000 Sep 21;407(6802):395-401.
2. Kanin EI, et al. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5812-7.
3. Liu Y, et al. Mol Cell Biol. 2004 Feb;24(4):1721-35.
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