15-LOX-1 inhibitor 5i

Chemical Structure : 15-LOX-1 inhibitor 5i

Catalog No.: PC-24322Not For Human Use, Lab Use Only.

15-LOX-1 inhibitor 5i is a potent, selective inhibitor of 15-lipoxygenase-1 (15-LOX-1) with IC50 of 1.7 uM, inhibits lipid peroxidation and protects cells from RSL3-induced cell death.

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Biological Activity

15-LOX-1 inhibitor 5i is a potent, selective inhibitor of 15-lipoxygenase-1 (15-LOX-1) with IC50 of 1.7 uM, inhibits lipid peroxidation and protects cells from RSL3-induced cell death.

Physicochemical Properties

M.Wt	354.92
Formula	C22H27ClN2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((6-chloro-2-phenyl-1H-indol-3-yl)methyl)heptan-1-amine

References

1. Zhang J, et al. Eur J Med Chem. 2025 Mar 19;290:117517.

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