1Ai-8214

Chemical Structure : 1Ai-8214

Catalog No.: PC-24690Not For Human Use, Lab Use Only.

1Ai-8214 is a small molecule inhibitor of RPS10-eIF1A interaction, binds both eIF1A and RPS10.

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Biological Activity

1Ai-8214 is a small molecule inhibitor of RPS10-eIF1A interaction, binds both eIF1A and RPS10.
1Ai-8214 decreases the development of ovarian cancer in OVCAR8 cell-derived xenograft (CDX) model.

Physicochemical Properties

M.Wt	366.80
Formula	C20H15ClN2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-chloro-4,5-dihydroxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

References

1. Hayat D, et al.EMBO J. 2025 May 12. doi: 10.1038/s44318-025-00449-6.

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1Ai-8214

Biological Activity

Physicochemical Properties

References

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