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2-Deoxy-D-glucose

Chemical Structure : 2-Deoxy-D-glucose

CAS No.: 154-17-6

2-Deoxy-D-glucose (2-DG, 2-Deoxy-D-arabino-hexose, 2-Deoxyglucose)

Catalog No.: PC-25406Not For Human Use, Lab Use Only.

2-Deoxy-D-glucose (2-DG, 2-Deoxyglucose) is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

2-Deoxy-D-glucose (2-DG, 2-Deoxyglucose) is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.

Physicochemical Properties

M.Wt 164.16
Formula C6H12O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3R,4S,5R)-3,4,5,6-Tetrahydroxyhexanal

References

1. Zhu Z, et al. Cancer Res. 2005 Aug 1;65(15):7023-30.

2. Miwa H, et al. Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose. Oncol Rep. 2013 May;29(5):2053-7.

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