2-PPA

Chemical Structure : 2-PPA

CAS No.: 21203-86-1

Catalog No.: PC-22928Not For Human Use, Lab Use Only.

2-PPA is a selective TMEM175 inhibitor with IC50 of 31 uM, 26-fold selectivity for TMEM175 compared to hKv3.1, increases lysosomal degradative activity.

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Biological Activity

2-PPA is a selective TMEM175 inhibitor with IC50 of 31 uM, 26-fold selectivity for TMEM175 compared to hKv3.1, increases lysosomal degradative activity.

Physicochemical Properties

M.Wt	170.22
Formula	C11H10N2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-phenylpyridin-4-ylamine

References

1. SeCheol Oh, et al. J Am Chem Soc. 2024 Aug 8. doi: 10.1021/jacs.4c05623.

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2-PPA

Biological Activity

Physicochemical Properties

References

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