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2-PPA

Chemical Structure : 2-PPA

CAS No.: 21203-86-1

2-PPA

Catalog No.: PC-22928Not For Human Use, Lab Use Only.

2-PPA is a selective TMEM175 inhibitor with IC50 of 31 uM, 26-fold selectivity for TMEM175 compared to hKv3.1, increases lysosomal degradative activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

2-PPA is a selective TMEM175 inhibitor with IC50 of 31 uM, 26-fold selectivity for TMEM175 compared to hKv3.1, increases lysosomal degradative activity.

Physicochemical Properties

M.Wt 170.22
Formula C11H10N2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-phenylpyridin-4-ylamine

References

1. SeCheol Oh, et al. J Am Chem Soc. 2024 Aug 8. doi: 10.1021/jacs.4c05623.

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