Chemical Structure : 2-arachidonoylglycerol
CAS No.: 53847-30-6
Catalog No.: PC-26931Not For Human Use, Lab Use Only.
2-arachidonoylglycerol (2-AG) is an endocannabinoid and potent, small molecule sperm calcium channel (CatSper) inhibitor, inhibits ICatSper with IC50 of 350 nM for outward currents and 670 nM for inward currents.
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2-arachidonoylglycerol (2-AG) is an endocannabinoid and potent, small molecule sperm calcium channel (CatSper) inhibitor, inhibits ICatSper with IC50 of 350 nM for outward currents and 670 nM for inward currents.
2-arachidonoylglycerol (2-AG) inhibitss mouse ICatSper but with less efficacy than it inhibits human ICatSper.
| M.Wt | 378.55 | |
| Formula | C23H38O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(5Z,8Z,11Z,14Z)-1,3-Dihydroxypropan-2-yl icosa-5,8,11,14-tetraenoate |
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1. Edwards M, et al. Hum Reprod. 2026 May 29:deag085.
2. Miller MR, et al. Science. 2016 Apr 29;352(6285):555-9.

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