Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-Calcium Channel -2-arachidonoylglycerol
2-arachidonoylglycerol

Chemical Structure : 2-arachidonoylglycerol

CAS No.: 53847-30-6

2-arachidonoylglycerol (2-AG, 2AG)

Catalog No.: PC-26931Not For Human Use, Lab Use Only.

2-arachidonoylglycerol (2-AG) is an endocannabinoid and potent, small molecule sperm calcium channel (CatSper) inhibitor, inhibits ICatSper with IC50 of 350 nM for outward currents and 670 nM for inward currents.

Packing Price Stock Quantity
5 mg $298 In stock
10 mg $488 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

2-arachidonoylglycerol (2-AG) is an endocannabinoid and potent, small molecule sperm calcium channel (CatSper) inhibitor, inhibits ICatSper with IC50 of 350 nM for outward currents and 670 nM for inward currents.
2-arachidonoylglycerol (2-AG) inhibitss mouse ICatSper but with less efficacy than it inhibits human ICatSper.

Physicochemical Properties

M.Wt 378.55
Formula C23H38O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(5Z,8Z,11Z,14Z)-1,3-Dihydroxypropan-2-yl icosa-5,8,11,14-tetraenoate

References

1. Edwards M, et al. Hum Reprod. 2026 May 29:deag085.

2. Miller MR, et al. Science. 2016 Apr 29;352(6285):555-9.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: