2GBI | Hv1 channel inhibitor | Probechem Biochemicals

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Chemical Structure : 2GBI

CAS No.: 5418-95-1

2GBI (2-guanidinobenzimidazole)

Catalog No.: PC-38295Not For Human Use, Lab Use Only.

2GBI (2-guanidinobenzimidazole) is a guanidine derivative that inhibits voltage-gated proton channel Hv1 by binding to the VSD from its intracellular side..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

2GBI (2-guanidinobenzimidazole) is a guanidine derivative that inhibits voltage-gated proton channel Hv1 by binding to the VSD from its intracellular side.

Physicochemical Properties

M.Wt	175.195
Formula	C8H9N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-guanidinobenzimidazole

References

1. Hong L, et al. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9971-6.

2. Gianti E, et al. Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8359-E8368.

3. Geragotelis AD, et al. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13490-13498.

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2GBI (2-guanidinobenzimidazole)

Biological Activity

Physicochemical Properties

References

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