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4-Demethylepipodophyllotoxin

Chemical Structure : 4-Demethylepipodophyllotoxin

CAS No.: 6559-91-7

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4-Demethylepipodophyllotoxin (4'-O-demethylepipodophyllotoxin, 4'-DMEP)

Catalog No.: PC-45256Not For Human Use, Lab Use Only.

4'-Demethylepipodophyllotoxin (4'-DMEP) is a potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.

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500 mg $138 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

4'-Demethylepipodophyllotoxin (4'-DMEP) is a potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.

Physicochemical Properties

M.Wt 400.3787
Formula C21H20O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR,9S)-

References

1. Dhawan D, et al. Carcinogenesis. 1999 Jun;20(6):997-1003.

2. Gewirtz DA. Cancer Res. 1985 Dec;45(12 Pt 1):6290-2.

3. Lee KH, et al. J Med Chem. 1990 May;33(5):1364-8.

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