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4-IBP

Chemical Structure : 4-IBP

CAS No.: 155798-08-6

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4-IBP (4 IBP;4IBP)

Catalog No.: PC-42070Not For Human Use, Lab Use Only.

4-IBP is a highly potent sigma receptor agonist with Ki of 1.7 nM and 25.2 nM for σ1 and σ2, respectively.

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50 mg $198 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

4-IBP is a highly potent sigma receptor agonist with Ki of 1.7 nM and 25.2 nM for σ1 and σ2, respectively.
4-IBP decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.

Physicochemical Properties

M.Wt 420.2873
Formula C19H21IN2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzamide, 4-iodo-N-[1-(phenylmethyl)-4-piperidinyl]-

References

1. John CS, et al. Cancer Res. 1995 Jul 15;55(14):3022-7.

2. Bermack JE, et al. Br J Pharmacol. 2001 Oct;134(3):691-9.

3. Mégalizzi V, et al. Neoplasia. 2007 May;9(5):358-69.

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