4-PPBP | Sigma 1 receptor agonist | Probechem Biochemicals

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Chemical Structure : 4-PPBP

CAS No.: 201216-39-9

4-PPBP (PPBP)

Catalog No.: PC-61602Not For Human Use, Lab Use Only.

4-PPBP is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.

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25 mg	$158	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

4-PPBP is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.
4-PPBP attenuates activity of neuronal nitric oxide synthase (nNOS), blunts ischemia-induced nitric oxide production, and provides neuroprotection in stroke models.

Physicochemical Properties

M.Wt	293.454
Formula	C21H27N
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-phenyl-1-(4-phenylbutyl) piperidine

References

1. Takahashi H, et al. Stroke. 1995 Sep;26(9):1676-82.

2. Narita N, et al. Eur J Pharmacol. 1995 Oct 6;293(3):277-80.

3. Yang ZJ, et al. Exp Neurol. 2010 Jan;221(1):166-74.

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4-PPBP (PPBP)

Biological Activity

Physicochemical Properties

References

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