5-Iodotubercidin | Adenosine kinase inhibitor

Chemical Structure : 5-Iodotubercidin

CAS No.: 24386–93-4

Catalog No.: PC-38793Not For Human Use, Lab Use Only.

5-Iodotubercidin (5-ITU) is a potent adenosine kinase (AdK) inhibitor with IC50 of 26 nM, also potently inhibits SARS-CoV-2 RNA synthesis.

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10 mg	$128	In stock
25 mg	$218	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

5-Iodotubercidin (5-ITU) is a potent adenosine kinase (AdK) inhibitor with IC50 of 26 nM, also potently inhibits SARS-CoV-2 RNA synthesis.

M.Wt	392.15
Formula	C11H13IN4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

1. Massillon D, et al. Biochem J. 1994 Apr 1;299 (Pt 1):123-8.

2. Ugarkar BG, et al. J Med Chem. 2000 Jul 27;43(15):2883-93.

3. García-Villafranca J, et al. Biochem Pharmacol. 2002 Jun 1;63(11):1997-2000.

4. Zhao J, et al. Antiviral Res. 2022 Feb;198:105254.