Chemical Structure : 5-Iodotubercidin
CAS No.: 24386–93-4
Catalog No.: PC-38793Not For Human Use, Lab Use Only.
5-Iodotubercidin (5-ITU) is a potent adenosine kinase (AdK) inhibitor with IC50 of 26 nM, also potently inhibits SARS-CoV-2 RNA synthesis.
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5-Iodotubercidin (5-ITU) is a potent adenosine kinase (AdK) inhibitor with IC50 of 26 nM, also potently inhibits SARS-CoV-2 RNA synthesis.
M.Wt | 392.15 | |
Formula | C11H13IN4O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
1. Massillon D, et al. Biochem J. 1994 Apr 1;299 (Pt 1):123-8.
2. Ugarkar BG, et al. J Med Chem. 2000 Jul 27;43(15):2883-93.
3. García-Villafranca J, et al. Biochem Pharmacol. 2002 Jun 1;63(11):1997-2000.
4. Zhao J, et al. Antiviral Res. 2022 Feb;198:105254.
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