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Chemical Structure : 5-NITP
Catalog No.: PC-62751Not For Human Use, Lab Use Only.
5-NITP is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression.
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5-NITP is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression.
| M.Wt | 518.2 | |
| Formula | C13H17N2O14P3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ahmad MF, et al. Mol Cancer Ther. 2012 Oct;11(10):2077-86.
2. Choi JS, et al. Cancer Res. 2018 Feb 15;78(4):1083-1096.
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