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5-OE-RU

Chemical Structure : 5-OE-RU

CAS No.: 1610526-17-4

5-OE-RU

Catalog No.: PC-27783Not For Human Use, Lab Use Only.

5-OE-RU is a natural product formed during bacterial synthesis of vitamin B2, potently activates mucosal associated invariant T (MAIT) cells and has immunomodulatory, inflammatory, and anticancer properties, binds to histocompatibility complex (MHC)-related protein MR1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

5-OE-RU is a natural product formed during bacterial synthesis of vitamin B2, potently activates mucosal associated invariant T (MAIT) cells and has immunomodulatory, inflammatory, and anticancer properties, binds to histocompatibility complex (MHC)-related protein MR1.

Physicochemical Properties

M.Wt 316.27
Formula C11H16N4O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

D-Ribitol, 1-deoxy-1-[[1,2,3,6-tetrahydro-2,6-dioxo-5-[(2-oxoethylidene)amino]-4-pyrimidinyl]amino]-

References

1. Corbett AJ, et al. Nature. 2014 May 15;509(7500):361-5.

2. Veerapen N, et al. Mol Immunol. 2021 Jan;129:114-120.

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