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6-Maleimidohexanoic acid N-hydroxysuccinimide ester

Chemical Structure : 6-Maleimidohexanoic acid N-hydroxysuccinimide ester

CAS No.: 55750-63-5

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6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS)

Catalog No.: PC-45996Not For Human Use, Lab Use Only.

A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity.

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50 mg $168 In stock
100 mg $254.4 In stock
500 mg $745 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity; a useful protective group in antibody drug conjugates.

Physicochemical Properties

M.Wt 308.2867
Formula C14H16N2O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester

References

1. Ehrlich GK, et al. Bioconjug Chem. 2013 Dec 18;24(12):2015-24.

2. Maeda M, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):621-4.

3. Kida S, et al. Bioorg Med Chem Lett. 2006 Feb;16(3):743-5.

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