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Chemical Structure : 680C91
CAS No.: 163239-22-3
Catalog No.: PC-49666Not For Human Use, Lab Use Only.
680C91 is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) with Ki of 51 nM.
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|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $258 | In stock | |
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680C91 is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) with Ki of 51 nM.
680C91 displays no activity against indoleamine 2,3-dioxygenase, monoamine oxidase A and B, 5-HT uptake or 5-HT1A, 1D, 2A and 2C receptors.
680C91 produces large increases in brain tryptophan and serotonin in vitro and in vivo in rats.
| M.Wt | 238.27 | |
| Formula | C15H11FN2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(E)-6-fluoro-3-[2-(3-pyridyl)vinyl]-1H-indole |
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1. Salter M, et al. Neuropharmacology. 1995 Feb;34(2):217-27.
2. Salter M, et al. Biochem Pharmacol. 1995 May 17;49(10):1435-42.
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