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7-Nitroindazole (7-NI)

Chemical Structure : 7-Nitroindazole (7-NI)

CAS No.: 2942-42-9

7-Nitroindazole (7-NI)

Catalog No.: PC-23711Not For Human Use, Lab Use Only.

7-Nitroindazole (7-NI) is a selective and BBB-penatrable inhibitor of nNOS, inhibits the activity of central NOS with an IC50 of 0.47 μM in the cerebellum of mice, has anti-injurious and neuroprotective properties.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

7-Nitroindazole (7-NI) is a selective and BBB-penatrable inhibitor of nNOS, inhibits the activity of central NOS with an IC50 of 0.47 μM in the cerebellum of mice, has anti-injurious and neuroprotective properties.

Physicochemical Properties

M.Wt 163.14
Formula C7H5N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-Nitro-1H-indazole

References

1. Moore PK, et al. Br J Pharmacol. 1993 Feb;108(2):296-7.

2. Memarpour S, et al. 2020 Nov;45(11):2775-2785.

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