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Chemical Structure : 709W92
Catalog No.: PC-49665Not For Human Use, Lab Use Only.
709W92 is a small molecule inhibitor of both tryptophan 2,3-dioxygenase (TDO) and 5-hydroxytryptamine (5-HT) reuptake, shows antidepressant efficacy.
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709W92 is a small molecule inhibitor of both tryptophan 2,3-dioxygenase (TDO) and 5-hydroxytryptamine (5-HT) reuptake, shows antidepressant efficacy.
709W92 potentiated head-twitch produced by 5-hydroxytryptophan, prevented head-twitch and whole brain 5-HT depletion produced by p-chloroamphetamine and rapidly decreased dorsal raphe firing.
709W92 showed anxiolytic activity in the rat-pup vocalization model of anxiety in vivo.
| M.Wt | 238.27 | |
| Formula | C15H11FN2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Salter M, et al. Neuropharmacology. 1995 Feb;34(2):217-27.
2. Salter M, et al. Adv Exp Med Biol. 1996;398:61-5.
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