Chemical Structure : 8-Nitrotryptanthrin
CAS No.: 77603-42-0
Catalog No.: PC-42226Not For Human Use, Lab Use Only.
8-Nitrotryptanthrin (GNF-PF-3777) is a potent human indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with Ki of 0.97 uM, also exhibits significant antitrypanosomal activities with EC50 of 0.82 uM.
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8-Nitrotryptanthrin (GNF-PF-3777) is a potent human indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with Ki of 0.97 uM, also exhibits significant antitrypanosomal activities with EC50 of 0.82 uM.
M.Wt | 293.2338 | |
Formula | C15H7N3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: 6.4 mg/mL (Need warming) |
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Chemical Name/SMILES |
Indolo[2,1-b]quinazoline-6,12-dione, 8-nitro- |
1. Li J, et al. Eur J Med Chem. 2016 Nov 10;123:171-179.
2. Scovill J, et al. Antimicrob Agents Chemother. 2002 Mar;46(3):882-3.
3. Hwang JM, et al. J Nat Prod. 2013 Mar 22;76(3):354-67.
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