Chemical Structure : A-1155463
CAS No.:
1235034-55-5
A-1155463
(A1155463;A 1155463)
Catalog No. : PC-45687Not For Human Use, Lab Use Only.
A-1155463 is a highly potent and selective BCL-XL inhibitor (Ki=10 pM).
Packing Price Stock Quantity 10 mg $178 In stock 0 1 2 3 4 5 25 mg $288 In stock 0 1 2 3 4 5 100 mg $658 In stock 0 1 2 3 4 5 200 mg Get quote 0 1 2 3 4 5 1 g Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4568701
Biological Activity
A-1155463 is a highly potent and selective BCL-XL inhibitor (Ki=10 pM).
Physicochemical Properties
M.Wt
669.7881
Formula
C35H32FN5O4S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 31 mg/mL
Chemical Name/SMILES
4-Thiazolecarboxylic acid, 2-[8-[(2-benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-5-[3-[4-[3-(dimethylamino)-1-propyn-1-yl]-2-fluorophenoxy]propyl]-
References
1. Tao ZF, et al. ACS Med Chem Lett.
2. Leverson JD, et al. Sci Transl Med.
3. Punnoose EA, et al. Mol Cancer Ther.
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