Catalog No.: PC-38443Not For Human Use, Lab Use Only.
A-286982 is a potent, nonpeptide inhibitor of LFA-1/ICAM-1 interaction with IC50 of 44 and 35 nM in LFA-1/ICAM-1 binding assay and LFA-1-mediated cellular adhesion assay, respectively.
A-286982 is a potent, nonpeptide inhibitor of LFA-1/ICAM-1 interaction with IC50 of 44 and 35 nM in LFA-1/ICAM-1 binding assay and LFA-1-mediated cellular adhesion assay, respectively.
The interaction between leukocyte function-associated antigen-1 (LFA-1), a member of the beta(2)-integrin family of adhesion molecules, and intracellular adhesion molecule ICAM-1 (CD54) is thought to play a critical role in the inflammatory process.
