Chemical Structure : A-61603
CAS No.: 107756-30-9
Catalog No.: PC-26581Not For Human Use, Lab Use Only.
A-61603 is a potent, selective alpha 1-adrenergic receptor (α1A AR) agonist, >35-fold more potent at α1A than at α1B or α1D sites, induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro with EC50 of 6.9 nM.
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A-61603 is a potent, selective alpha 1-adrenergic receptor (α1A AR) agonist, >35-fold more potent at α1A than at α1B or α1D sites, induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro with EC50 of 6.9 nM.
| M.Wt | 390.30 | |
| Formula | C14H20BrN3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)methanesulfonamide hydrobromide |
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1. Knepper SM, et al. J Pharmacol Exp Ther. 1995 Jul;274(1):97-103.
2. Buckner SA, et al. Eur J Pharmacol. 1996 Feb 22;297(3):241-8.

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