Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : A-943931 dihydrochloride
Catalog No.: PC-63419Not For Human Use, Lab Use Only.
A-943931 dihydrochloride is a potent, selective antagonist of histamine H4 receptor (H4R) with binding pKi of 8.33 and 8.42 for hH4 and rH4, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A-943931 dihydrochloride is a potent, selective antagonist of histamine H4 receptor (H4R) with binding pKi of 8.33 and 8.42 for hH4 and rH4, respectively.
A-943931displays >150-fold selectivity over H1, H2 and H3 receptors.
A-943931 potently inhibits zymosan-induced peritonitis in mice with ED50 of 34 umol/kg.
| M.Wt | 368.306 | |
| Formula | C17H23Cl2N5 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Cowart MD, et al. J Med Chem. 2008 Oct 23;51(20):6547-57.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
