A 77-01 | ALK5 inhibitor | Probechem Biochemicals

Chemical Structure : A 77-01

CAS No.: 607737-87-1

A 77-01 (A77-01, A-77-01)

Catalog No.: PC-45993Not For Human Use, Lab Use Only.

A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
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Biological Activity

A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
A-77-01 is a close analogue of A-83-01(Axon 1421) and has a very similar biological profile of A-83-01.

Physicochemical Properties

M.Wt	286.3306
Formula	C18H14N4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Quinoline, 4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-

References

1. Tojo M, et al. Cancer Sci. 2005 Nov;96(11):791-800.

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A 77-01 (A77-01, A-77-01)

Biological Activity

Physicochemical Properties

References

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