Catalog No.: PC-35279Not For Human Use, Lab Use Only.
ABC99 (NOTUM inhibitor ABC99) is a potent, selective inhibitor of the Wnt-deacylating enzyme serine hydrolase NOTUM with IC50 of 13 nM, shows excellent selectivity across the serine hydrolase family.
ABC99 (NOTUM inhibitor ABC99) is a potent, selective inhibitor of the Wnt-deacylating enzyme serine hydrolase NOTUM with IC50 of 13 nM, shows excellent selectivity across the serine hydrolase family.
NOTUM inhibitor ABC99 preserves Wnt-mediated cell signaling in the presence of NOTUM in a concentration-dependent manner (IC50=89 nM) as measured using a Super TOPflash assay.
