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Chemical Structure : ABH hydrochloride
CAS No.: 194656-75-2
Catalog No.: PC-70087Not For Human Use, Lab Use Only.
ABH hydrochloride is a potent, selective human Arginase inhibitor with Ki of 0.25 uM (pH=7.5), 8.5 nM (pH=9.5) for type II arginase.
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|---|---|---|---|
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| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
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ABH hydrochloride is a potent, selective human Arginase inhibitor with Ki of 0.25 uM (pH=7.5), 8.5 nM (pH=9.5) for type II arginase.
ABH hydrochloride inhibits the LPS-induced increases in pulmonary IL-8, neutrophils, and goblet cells as well as airway fibrosis.
ABH hydrochloride prevents LPS-induced right ventricular hypertrophy, indicative of pulmonary hypertension in a guinea pig model of COPD.
| M.Wt | 211.45 | |
| Formula | C6H14BNO4 · HCl | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-2-amino-6-boronohexanoic acid hydrochloride |
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1. Colleluori DM, et al. Biochemistry. 2001 Aug 7;40(31):9356-62.
2. Baggio R, et al. J Pharmacol Exp Ther. 1999 Sep;290(3):1409-16.
3. Pera T, et al. J Pharmacol Exp Ther. 2014 May;349(2):229-38.
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