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ABT-002

Chemical Structure : ABT-002

CAS No.: 2438239-83-7

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ABT-002 (ABT002)

Catalog No.: PC-25336Not For Human Use, Lab Use Only.

ABT-002 is the active metabolite of ABS-752, a potent molecular glue degrader of GSPT1 and NEK7, impairs the viability of HCC cell lines.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ABT-002 is the active metabolite of ABS-752, a potent molecular glue degrader of GSPT1 and NEK7, impairs the viability of HCC cell lines.

Physicochemical Properties

M.Wt 306.25
Formula C14H11FN2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1-oxoisoindoline-5-carboxylic acid

References

1. Glaza P, et al. Commun Chem. 2025 Aug 14;8(1):247.

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