Chemical Structure : ABT-288
CAS No.:
948845-91-8
ABT-288
(ABT288)
Catalog No. : PC-63032Not For Human Use, Lab Use Only.
ABT-288 is a potent, selective and competitive antagonist of H3 receptor with Ki of 1.9/8.2 nM for human/rat H3 respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6303201
Biological Activity
ABT-288 is a potent, selective and competitive antagonist of H3 receptor with Ki of 1.9/8.2 nM for human/rat H3 respectively.
Physicochemical Properties
M.Wt
372.472
Formula
C23H24N4O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-[4'-((3aR,6aR)-5-methyl-hexahydro-pyrrolo[3,4-b]pyrrol-1-yl)-biphenyl-4-yl]-2H-pyridazin-3-one
References
1. Esbenshade TA, et al. J Pharmacol Exp Ther.
2. Hudzik TJ, et al. Psychopharmacology (Berl).
3. Othman AA, et al. Br J Clin Pharmacol.
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