ABT-384 | 11β-HSD1 inhibitor | Probechem Biochemicals

Chemical Structure : ABT-384

CAS No.: 868623-40-9

ABT-384 (ABT384)

Catalog No.: PC-21935Not For Human Use, Lab Use Only.

ABT-384 is a potent and selective inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with Ki values of 0.1-2.7 nM against rodent, monkey, and human 11β-HSD1.

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10 mg	$458	In stock
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Biological Activity

ABT-384 is a potent and selective inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with Ki values of 0.1-2.7 nM against rodent, monkey, and human 11β-HSD1.

Physicochemical Properties

M.Wt	493.58
Formula	C25H34F3N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Piperazineacetamide, N-[5-(aminocarbonyl)tricyclo[3.3.1.13,7]dec-2-yl]-alpha,alpha-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-,

References

1. An G, et al. Drug Metab Dispos. 2013 May;41(5):1035-45.

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ABT-384 (ABT384)

Biological Activity

Physicochemical Properties

References

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