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Chemical Structure : ABT-751
CAS No.: 141430-65-1
Catalog No.: PC-43449Not For Human Use, Lab Use Only.
ABT-751 (E7010) is an orally active antimitotic agent that inhibits tubulin polymerization, exhibits consistent growth-inhibitory activities against a panel of human tumor cell lines (IC50=0.06-0.8 ug/mL).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $68 | In stock | |
| 25 mg | $118 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $298 | In stock | |
| 250 mg | Get quote |
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ABT-751 (E7010) is an orally active antimitotic agent that inhibits tubulin polymerization, exhibits consistent growth-inhibitory activities against a panel of human tumor cell lines (IC50=0.06-0.8 ug/mL).
ABT-751 shows good antitumor activity against various rodent tumors and human tumor xenografts,
| M.Wt | 371.41 | |
| Formula | C18H17N3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 48 mg/mL |
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| Chemical Name/SMILES |
Benzenesulfonamide, N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxy- |
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1. Koyanagi N, et al. Cancer Res. 1994 Apr 1;54(7):1702-6.
2. Yoshimatsu K, et al. Cancer Res. 1997 Aug 1;57(15):3208-13.
3. Segreti JA, et al. Cancer Chemother Pharmacol. 2004 Sep;54(3):273-81.
4. Yoshimatsu K, et al. Cancer Res. 1997 Aug 1;57(15):3208-13.
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