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Chemical Structure : AC-260584
CAS No.: 560083-42-3
Catalog No.: PC-42101Not For Human Use, Lab Use Only.
AC-260584 is a potent, selective, allosteric muscarinic M1 receptor agonist with pEC50 of 8.1, 7.6, 8.3 and 6.6 for WT M1, TM3 mutant W101A, L102A, and Y106A, repespectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $258 | In stock | |
| 10 mg | $398 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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AC-260584 is a potent, selective, allosteric muscarinic M1 receptor agonist with pEC50 of 8.1, 7.6, 8.3 and 6.6 for WT M1, TM3 mutant W101A, L102A, and Y106A, repespectively.
AC-260584 increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus.
| M.Wt | 348.4549 | |
| Formula | C20H29FN2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2H-1,4-Benzoxazin-3(4H)-one, 4-[3-(4-butyl-1-piperidinyl)propyl]-7-fluoro- |
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1. Li Z, et al. Eur J Pharmacol. 2007 Oct 31;572(2-3):129-37.
2. Spalding TA, et al. Mol Pharmacol. 2006 Dec;70(6):1974-83.
3. Li Z, et al. Eur J Pharmacol. 2008 Oct 31;596(1-3):89-97.
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