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AC-263093

Chemical Structure : AC-263093

CAS No.: 849459-86-5

AC-263093 (AC263093)

Catalog No.: PC-35865Not For Human Use, Lab Use Only.

AC-263093 (AC263093) is a potent, functionally selective neuropeptide FF receptor type 2 (NPFFR2) agonist with pKi of 6.9.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AC-263093 (AC263093) is a potent, functionally selective neuropeptide FF receptor type 2 (NPFFR2) agonist with pKi of 6.9; shows equal affinity for NPFFR1 and NPFFR2, and functionally inactivated NPFFR1; attenuates morphine tolerance in vivo.

Physicochemical Properties

M.Wt 319.988
Formula C8H8Br2N4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3,4-dibromobenzylidene)hydrazine-1-carboximidamide

References

1. Malin DH, et al. Neurosci Lett. 2015 Jan 1;584:141-5.

2. Lin YT, et al. Exp Neurol. 2017 May;291:62-73.

3. Lin YT, et al. Eur J Pain. 2016 Jul;20(6):895-906.

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