AC-42 | M1 mAChR agonist | Probechem Biochemicals

Chemical Structure : AC-42

AC-42 (M1 muscarinic receptor agonist)

Catalog No.: PC-24783Not For Human Use, Lab Use Only.

AC-42 is a poent selective allosteric agonist of M1 muscarinic receptor with EC50 of 805 nM and 220 nM for human wild-type and Y381A mutated M1 receptors, respectively.

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Biological Activity

AC-42 is a poent selective allosteric agonist of M1 muscarinic receptor with EC50 of 805 nM and 220 nM for human wild-type and Y381A mutated M1 receptors, respectively.

Physicochemical Properties

M.Wt	301.47
Formula	C20H31NO
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Butanone, 4-(4-butyl-1-piperidinyl)-1-(2-methylphenyl)-

References

1. Marlene A Jacobson, et al. Mol Pharmacol. 2010 Oct;78(4):648-57.

2. Langmead CJ, et al. Mol Pharmacol. 2006 Jan;69(1):236-46.

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AC-42 (M1 muscarinic receptor agonist)

Biological Activity

Physicochemical Properties

References

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