ACR-895 | RhoA inhibitor | Probechem Biochemicals

Chemical Structure : ACR-895

ACR-895 (ACR895)

Catalog No.: PC-28591Not For Human Use, Lab Use Only.

ACR-895 is a covalent small molecule inhibitor of Rho family GTPase RhoA protein by covalent modification of Cys107, inhibits RhoA C190S nucleotide exchange with IC50 of 20 uM.

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Biological Activity

ACR-895 is a covalent small molecule inhibitor of Rho family GTPase RhoA protein by covalent modification of Cys107, inhibits RhoA C190S nucleotide exchange with IC50 of 20 uM.

Physicochemical Properties

M.Wt	229.28
Formula	C14H15NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2-ethyl-6-methyl-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)prop-2-yn-1-one

References

1. Muhammad S Hussain, et al. ACS Chem Neurosci. 2023 Jul 19;14(14):2509-2516.

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ACR-895 (ACR895)

Biological Activity

Physicochemical Properties

References

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