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Chemical Structure : ACT-774312
Catalog No.: PC-20093Not For Human Use, Lab Use Only.
ACT-774312 (ACT774312) is a potent and selective CRTH2 receptor antagonist with IC50 of 3 nM, 150-fold more potent than setipiprant in inhibiting PGD2-induced eosinophil cell shape change.
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ACT-774312 (ACT774312) is a potent and selective CRTH2 receptor antagonist with IC50 of 3 nM, 150-fold more potent than setipiprant in inhibiting PGD2-induced eosinophil cell shape change.
| M.Wt | 389.82 | |
| Formula | C18H17ClFN5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Aissaoui H, et al. ChemMedChem. 2023 Mar 8:e202300007.
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