ACY-1083 | HDAC6 inhibitor | Probechem Biochemicals

Chemical Structure : ACY-1083

CAS No.: 1708113-43-2

ACY-1083 (ACY1083)

Catalog No.: PC-24775Not For Human Use, Lab Use Only.

ACY-1083 is a potent, selective and brain-penetrating HDAC6 inhibitor with IC50 of 3 nM, >250-fold more selective for HDAC6 than all other classes of HDAC isoforms.

Packing	Price	Stock
2 mg	$188	In stock
5 mg	$298	In stock
10 mg	$498	In stock
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Biological Activity

ACY-1083 is a potent, selective and brain-penetrating HDAC6 inhibitor with IC50 of 3 nM, >250-fold more selective for HDAC6 than all other classes of HDAC isoforms.

Physicochemical Properties

M.Wt	348.35
Formula	C17H18F2N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4,4-Difluoro-1-phenylcyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide

References

1. Barbara Vergani, et al. J Med Chem. 2019 Dec 12;62(23):10711-10739.

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ACY-1083 (ACY1083)

Biological Activity

Physicochemical Properties

References

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