ADS10227

Chemical Structure : ADS10227

Catalog No.: PC-23594Not For Human Use, Lab Use Only.

ADS10227 is a potent muscarinic receptor antagonist with binding Ki of 2.8 nM and 5.1 nM for human muscarinic M2 and M4 receptors (hM2R and hM4R) respectively.

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Biological Activity

ADS10227 is a potent muscarinic receptor antagonist with binding Ki of 2.8 nM and 5.1 nM for human muscarinic M2 and M4 receptors (hM2R and hM4R) respectively.

Physicochemical Properties

M.Wt	491.72
Formula	C30H45N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-{4-{4-{[4-(phenoxymethyl)cyclohexyl]methyl}piperazin-1-yl}but-1-yl}-1-(benzyl)guanidine

References

1. Staszewski M, et al. ACS Chem Neurosci. 2021 Jul 7;12(13):2503-2519.

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ADS10227

Biological Activity

Physicochemical Properties

References

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