AEP07 PARP4 inhibitor | PARP4 inhibitor

Chemical Structure : AEP07

AEP07 (PARP4 inhibitor AEP 07)

Catalog No.: PC-72698Not For Human Use, Lab Use Only.

AEP07 (AEP 07) is a selective small molecule inhibitor of PARP4 (vPARP) inhibitor with IC50 of 0.8 uM, >12-fold selective over other PARP family members.

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Biological Activity

AEP07 (AEP 07) is a selective small molecule inhibitor of PARP4 (vPARP) inhibitor with IC50 of 0.8 uM, >12-fold selective over other PARP family members.

Physicochemical Properties

M.Wt	452.266
Formula	C17H13IN2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(((6-iodo-8-methyl-4-oxo-3,4-dihydroquinazolin-2-yl)methyl)thio)benzoic acid

References

1. Ilsa T Kirby, et al. RSC Med Chem. 2021 Oct 4;12(11):1950-1957.

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AEP07 (PARP4 inhibitor AEP 07)

Biological Activity

Physicochemical Properties

References

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