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AF-2112

Chemical Structure : AF-2112

CAS No.:

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AF-2112 (AF2112)

Catalog No.: PC-21253Not For Human Use, Lab Use Only.

AF-2112 is a small molecule inhibitor of TEAD, reduces the expression of CTGF, Cyr61, Axl and NF2, inhibits migration of human MDA-MB-231 breast cancer cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AF-2112 is a small molecule inhibitor of TEAD, reduces the expression of CTGF, Cyr61, Axl and NF2, inhibits migration of human MDA-MB-231 breast cancer cells.

Physicochemical Properties

M.Wt 351.38
Formula C21H18FNO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO
Chemical Name/SMILES

4-fluoro-2-((3-phenethoxyphenyl)amino)benzoic acid

References

1. Ahmed Fnaiche, et al. Bioorg Med Chem Lett. 2023 Oct 15:95:129488.

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