Chemical Structure : AGN192836
Catalog No.: PC-35360Not For Human Use, Lab Use Only.
AGN192836 (AGN 192836) is a potent, selective α2 adrenergic (alpha 2-adrenoceptor) agonist with EC50 of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively.
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AGN192836 (AGN 192836) is a potent, selective α2 adrenergic (alpha 2-adrenoceptor) agonist with EC50 of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively; displays 1200-, 50- and 10-fols selectivity for the α2A-receptor, α2B-receptor, and α2C-receptors relative to the α2C-receptors; demonstrates effectivity for the reduction of intraocular pressure and for the reduction of blood pressure in vivo.
M.Wt | 231.255 | |
Formula | C12H13N3O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Munk SA, et al. J Med Chem. 1997 Jan 3;40(1):18-23.
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