Chemical Structure : AH-23848 calcium salt
Catalog No.: PC-70016Not For Human Use, Lab Use Only.
AH-23848 calcium salt is a dual antagonist of TP1 and EP4 receptors that inhibit TXA2-induced platelet aggregation with IC50 of 0.26 uM.
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AH-23848 calcium salt is a dual antagonist of TP1 and EP4 receptors that inhibit TXA2-induced platelet aggregation with IC50 of 0.26 uM.
AH-23848 impairs PGE2-mediated relaxation of piglet saphenous vein by antagonizing the PGE2 receptor EP4.
M.Wt | 496.6 | |
Formula | C29H34NO5 • 1/2Ca | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Brittain RT, et al. Circulation. 1985 Dec;72(6):1208-18.
2. Coker SJ, et al. Br J Pharmacol. 1985 Sep;86(1):259-64.
3. Qian X, et al. J Biol Chem. 2011 Jan 21;286(3):2111-20.
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