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Chemical Structure : AH6809
CAS No.: 33458-93-4
Catalog No.: PC-42574Not For Human Use, Lab Use Only.
AH6809 is a xanthone derivative that fuctions as an EP and DP receptor antagonist with Ki of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | $528 | In stock | |
| 250 mg | Get quote |
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AH6809 is a xanthone derivative that fuctions as an EP and DP receptor antagonist with Ki of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively.
AH6809 blocks the PGE2-induced accumulation of cAMP in COS cells transfected with the human EP2 receptor。
AH6809 is an effective antagonist antiaggregatory actions of PGD2, but not PGI2, with EC50 50 uM in whole human platelet.
| M.Wt | 298.2901 | |
| Formula | C17H14O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
9H-Xanthene-2-carboxylic acid, 6-(1-methylethoxy)-9-oxo- |
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1. Armstrong RA, et al. Br J Pharmacol. 1986 Mar;87(3):543-51.
2. Woodward DF, et al. Biochem Pharmacol. 1995 Nov 9;50(10):1731-3.
3. Keery RJ, et al. Br J Pharmacol. 1988 Jul;94(3):745-54.
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