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Chemical Structure : AICP
Catalog No.: PC-60783Not For Human Use, Lab Use Only.
AICP is a potent, selective GluN2C-selective NMDA receptor glycine site superagonist with EC50 of 1.7 nM at GluN1/2C.
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AICP is a potent, selective GluN2C-selective NMDA receptor glycine site superagonist with EC50 of 1.7 nM at GluN1/2C.
AICP is a full agonist at GluN1/2A (100% response compared with glycine), a partial agonist at GluN1/2B and GluN1/2D (10% and 27%, respectively), and a highly efficacious superagonist at GluN1/2C receptors (353%).
AICP selectively enhances responses from recombinant GluN1/2C receptors in the presence of physiological glycine concentrations.
| M.Wt | 351.406 | |
| Formula | C20H21N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jessen M, et al. Mol Pharmacol. 2017 Aug;92(2):151-161.
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