AIP-II

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Chemical Structure : AIP-II

CAS No.: 200010-31-7

Catalog No.: PC-26865Not For Human Use, Lab Use Only.

AIP-II is a peptidomimetic inhibitor of staphylococcus aureus AgrC quorum sensing receptors, inhibits AgrC-III in methicillin-resistant type III Staphylococcus aureus strain AH1747 with IC50 of 0.532 nM, binds to the AgrC-II receptor and regulates virulence gene expression in Staphylococcus aureus.

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10 mg	$458	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	878.99
Formula	C38H58N10O12S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	L-Phenylalanine, glycyl-L-valyl-L-asparaginyl-L-alanyl-L-cysteinyl-L-seryl-L-seryl-L-leucyl-, (9→5)-thiolactone

References

1. Wang B, et al. Mol Cell. 2014 Mar 20;53(6):929-40.

2. Olson ME, et al. J Bacteriol. 2014 Oct;196(19):3482-93.

3. Brown MM, et al. Antimicrob Agents Chemother. 2020 May 21;64(6):e00172-20.

4. Vasquez JK, et al. Chembiochem. 2017 Feb 16;18(4):413-423.

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AIP-II

Biological Activity

Physicochemical Properties

References

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